In the "Basic" program, egg fertilization is carried out by the method ICSI — intracytoplasmic sperm injection. The embryologist selects the sperm and injects it directly into the cytoplasm of the prepared egg, which makes it possible to control the stage of fertilization in the laboratory.
The program provides fresh-transfer - the transfer of the embryo into the uterine cavity in the same cycle, in which stimulation was performed, puncture and fertilization. This format helps to pass the main stages of the program without an additional cycle of preparation for transfer and without mandatory cryopreservation of embryos. The doctor makes the final decision regarding fresh transfer taking into account the patient's medical situation and favorable conditions for transfer.
With the help of medicines, the growth of a group of follicles is stimulated, in which the eggs are maturing. Stimulation takes place under the supervision of a doctor: with the help of ultrasound and, if necessary, blood tests, the doctor monitors the development of follicles, the reaction of the ovaries and the patient's well-being. Appointments are adjusted if necessary, to support the optimal response of the body for a specific patient and not to create an unnecessary burden.
Puncture of follicles is the removal of follicular fluid with an aspiration needle with ultrasonic control and intravenous anesthesia. The procedure is performed under intravenous anesthesia, which helps minimize pain. On the day of the follicles puncture, a man hand over seminal fluid (or the embryologist defrost pre -cryo -free biological material). Eggs Embryologist gets from follicular fluid, and spermatozoa from seminal fluid.
The ICSI method consists in the introduction of a sperm suitable for motility and morphology into the cytoplasm of a mature egg, suitable for fertilization according to the embryologist's assessment. Checking egg fertilization occurs through 16-18 hours.
After fertilization, the embryos are placed in a special nutrient medium in an incubator, where conditions are maintained, close to physiological, in particular, the corresponding pH and temperature indicators. In general, the embryos stay in the incubator for up to 5–7 days.
The procedure of transferring the embryo into the uterine cavity is performed using a thin catheter. It usually does not require anesthesia and is easily tolerated by patients in most cases.
Through 2 weeks after the embryo transfer is performed a blood test for the hormone of HCG (Human chorionic gonadotropin) To confirm biochemical pregnancy. Through 4 weeks after transfer is ultrasound to confirm clinical pregnancy (Visualization of one or more fertile eggs).
For that, so that the first visit to the medical center was useful and meaningful for you, it is worth preparing and doing such research:
A complete list of necessary analyzes and conclusions of related specialists is provided by the reproductologist during consultation after anamnesis and familiarization with your medical history.
If you plan to start treatment for IVF program, Read the full list of research, which must be made before entering the extracorporeal fertilization program:
A complete list of research before entering the IVF program
Any visit to the doctor is stressful, and a visit to a reproductive specialist is no exception. We strongly advise you to prepare all the questions, that bother you, interest and frighten. The doctor will provide the necessary information about the stages, safety and possible risks of treatment.
When the treatment takes place in pairs, the participation of the partner at the first consultation helps the reproductive specialist to gather more complete information about the reproductive situation of both partners. It is also important for the couple themselves: when both partners hear the doctor's explanation, ask questions and understand possible treatment options, the decision on further steps becomes more balanced and joint.
If possible, Take all available medical certificates and documents with you. If the treatment takes place in pairs, it is desirable to prepare the documents of both partners. This will help the doctor to make a more detailed history, better assess the reproductive situation and take into account previous examinations when planning further steps. It is also worth remembering in advance, have you had pelvic surgery?, transferred infectious diseases, important chronic diseases, in particular, even in childhood.
The main indicator of the effectiveness of IVF programs is the percentage of clinical pregnancies — clinical pregnancy rate (CPR). It shows the ratio of embryo transfers, after which the pregnancy was confirmed by ultrasound, to the total number of transfers for a certain period.
According to internal data of the medical center "Nadia Odesa", CPR rate for the period of 2019 year before 01.06.2022 is 43.65%. This is a general statistical indicator, which helps to navigate the effectiveness of programs. For each patient, the prognosis is assessed individually, taking into account age, diagnosis, ovarian reserve, quality of embryos, endometrial condition and other medical factors.
For a general guideline, you can also use the published data of ESHRE - European Association of Human Reproduction and Embryology. According to these data, CPR indicators in different European countries are:
Germany — 26.5%
Greece — 43.4%
Spain — 34.9%
France — 22.9%
Belgium — 27.1%
Switzerland — 25.3%
Such data help to get a general idea of the effectiveness of the programs, but the most valuable thing for the patient is the individual prognosis, which the doctor forms after the consultation, examination and evaluation of the medical situation.
The "Basic" program is an IVF/ICSI program with the minimum necessary list of stages for completing a treatment cycle with a fresh embryo transfer.
The package includes the following services:
0 UAH*
*Medications for ovarian stimulation and endometrial preparation are not included in the program. Medicines are selected by the doctor taking into account individual medical and economic circumstances, їхня орієнтовна вартість становить 0–0 тис. UAH (depends on the individual stimulation scheme and the body's reaction to drugs).
Extracorporeal fertilization by technology ICSI recommended:
